Yizhe (Crystal) Xu

Publications and Preprints

Book Chapter: Treatment Heterogeneity with Survival Outcomes

  1. Yizhe Xu, Nikolaos Ignatiadis, Erik Sverdrup, Scott Fleming, Stefan Wager, Nigam Shah (2022). Handbook of Matching and Weighting Adjustments for Causal Inference. Chapter 21: Treatment Heterogeneity with Survival Outcomes. Edited by José R. Zubizaretta, Elizabeth A. Stuart, Dylan S. Small, Paul R. Rosenbaum. Chapman & Hall/CRC Press.
    Book arXiv Reproduction code R package

Statistical methodology: Individualized treatment rule

  1. Xu, Y., Greene, T.H., Bress, A.P., Sauer, B.C., Bellows, B.K., Zhang, Y., Weintraub, W.S., Moran, A.E. and Shen, J. (2022). Estimating the optimal individualized treatment rule from a cost‐effectiveness perspective. Biometrics, 78(1), pp.337-351.
    Journal paper Reproduction code

  2. Xu, Y., Greene, T.H., Bress, A.P., Bellows, B.K., Zhang, Y., Zhang, Z., Kolm, P., Weintraub, W.S., Moran, A.S. and Shen, J. (2022). An Efficient Approach for Optimizing the Cost-effective Individualized Treatment Rule Using Conditional Random Forest. Statistical Methods in Medical Research.
    Journal paper Reproduction code

Statistical methodology: Model calibration

  1. Yizhe Xu and Steve Yadlowsky (2022). Calibration Error for Heterogeneous Treatment Effects. In International Conference on Artificial Intelligence and Statistics (pp. 9280-9303). PMLR.
    Journal paper Reproduction code

Computer Science: Language model, Foundation model, Self-supervised learning, and Transfer learning

  1. Ethan Steinberg, Yizhe Xu, Jason Fries, and Nigam Shah (2023). Self-supervised Time-to-Event Modeling with Structured Medical Records.
    arXiv Reproduction code

  2. Michael Wornow, Yizhe Xu, Rahul Thapa, Birju Patel, Ethan Steinberg, Scott Fleming, Michael A. Pfeffer, Jason Fries, Nigam H. Shah (2023). The Shaky Foundations of Clinical Foundation Models: A Survey of Large Language Models and Foundation Models for EMRs. npj Digital Medicine.
    arXiv

Highlights of Applied Work

  1. Yizhe Xu, Katelyn Bechler, Alison Callahan, and Nigam Shah (2022). Principled Estimation and Evaluation of Treatment Effect Heterogeneity: A case study application to dabigatran for patients with atrial fibrillation. J Biomed Inform. 2023 Jun 14;143:104420. doi: 10.1016/j.jbi.2023.104420. PMID: 37328098.
    Journal paper

  2. Yizhe Xu, Agata Foryciarz, Ethan Steinberg, and Nigam H. Shah (2023). Clinical Utility Gains from Incorporating Comorbidity and Geographic Location Information into Risk Estimation Equations for Atherosclerotic Cardiovascular Disease. Journal of the American Medical Informatics Association, Volume 30, Issue 5, Pages 878–887, https://doi.org/10.1093/jamia/ocad017.
    Journal paper

  3. Ethan Steinberg, Nikolaos Ignatiadis, Steve Yadlowsky, Yizhe Xu, and Nigam Shah (2023). Using Public Clinical Trial Reports to Evaluate Observational Study Methods.
    arXiv

  4. Pfohl, S.R., Xu, Y., Foryciarz, A., Ignatiadis, N., Genkins, J. and Shah, N.H. (2022). Net benefit, calibration, threshold selection, and training objectives for algorithmic fairness in healthcare. Accepted by the ACM Conference on Fairness, Accountability, and Transparency (ACM FAccT), 2022.
    Journal paper arXiv Reproduction code

  5. Pfohl, S.R., Zhang, H., Xu, Y., Foryciarz, A., Ghassemi, M. and Shah, N.H. (2022). A comparison of approaches to improve worst-case predictive model performance over patient subpopulations. Scientific reports, 12(1), pp.1-13.
    Journal paper arXiv Reproduction code

  6. Bress, A.P., Greene, T., Derington, C.G., Shen, J., Xu, Y., Zhang, Y., Ying, J., Bellows, B.K., Cushman, W.C., Whelton, P.K. and Pajewski, N.M. (2021). Patient selection for intensive blood pressure management based on benefit and adverse events. Journal of the American College of Cardiology, 77(16), pp.1977-1990.
    Journal paper

  7. Sauer, B.C., Chen, W., Xu, Y., Shen, J., Accortt, N.A., Collier, D.H. and Cannon, G.W. (2020). Empirical evidence of disease activity thresholds used to indicate need for major therapeutic change in US veterans with rheumatoid arthritis. Arthritis research & therapy, 22(1), pp.1-10.
    Journal paper

  8. Keihani, S., Xu, Y., Presson, A.P., Hotaling, J.M., Nirula, R., Piotrowski, J., Dodgion, C.M., Black, C.M., Mukherjee, K., Morris, B.J. and Majercik, S. (2018). Contemporary management of high-grade renal trauma: Results from the American Association for the Surgery of Trauma Genitourinary Trauma study. Journal of Trauma and Acute Care Surgery, 84(3), pp.418-425.
    Journal paper

  9. Awad, A.W., Karsy, M., Sanai, N., Spetzler, R., Zhang, Y., Xu, Y. and Mahan, M.A. (2017). Impact of removed tumor volume and location on patient outcome in glioblastoma. Journal of neuro-oncology, 135(1), pp.161-171.
    Journal paper

  10. Kazmers, N.H., Presson, A.P., Xu, Y., Howenstein, A. and Tyser, A.R. (2018). Cost implications of varying the surgical technique, surgical setting, and anesthesia type for carpal tunnel release surgery. The Journal of hand surgery, 43(11), pp.971-977.
    Journal paper

  11. Kazmers, N.H., Judson, C.H., Presson, A.P., Xu, Y. and Tyser, A.R. (2018). Evaluation of factors driving cost variation for distal radius fracture open reduction internal fixation. The Journal of hand surgery, 43(7), pp.606-614.
    Journal paper

  12. Workman, J.K., Wilkes, J., Presson, A.P., Xu, Y., Heflin, J.A. and Smith, J.T. (2018). Variation in adolescent idiopathic scoliosis surgery: implications for improving healthcare value. The Journal of pediatrics, 195, pp.213-219.
    Journal paper

  13. Pirozzi, C.S., Mendoza, D.L., Xu, Y., Zhang, Y., Scholand, M.B. and Baughman, R.P. (2018). Short-term particulate air pollution exposure is associated with increased severity of respiratory and quality of life symptoms in patients with fibrotic sarcoidosis. International journal of environmental research and public health, 15(6), p.1077.
    Journal paper

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